Rationale and design of the NO-PARTY trial: Near-zero fluoroscopic exposure during catheter ablation of supraventricular arrhythmias in young patients

In plain language

This paper describes a planned randomised trial of 210 young patients. It compares standard catheter ablation with 3D mapping-guided near-zero-fluoroscopy ablation, with patient dose as the primary measure and operator dose as a secondary one. It reports no results.

At a glance

Type of study: Original research, Randomized trial
Who was studied: Patients, Electrophysiologists
Topics: Patient dose Dose reduction techniques DNA and cellular effects Dosimetry and monitoring
Summary based on: the abstract

What it found

Planned multicentre randomised trial comparing conventional catheter ablation with EnSite NavX-guided ablation of supraventricular tachyarrhythmias. This design paper reports no results.
Key figures: 210 patients (planned)
The primary end-point is reduction in patient radiation dose. Reduction in operator radiation dose is a secondary end-point.
A subgroup of patients will be assessed for acute chromosomal DNA damage in lymphocytes to evaluate the radiobiological effect of dose reduction.

Limits to keep in mind

This is a protocol and rationale paper with no results, and operator dose is only a secondary end-point. Countries and participating centres are not stated in the abstract.

Radiation-Induced Noncancer Risks in Interventional Cardiology: Optimisation of Procedures and Staff and Patient Dose Reduction (2013, Narrative review)
Fluoroscopy-minimization strategy for catheter ablation of Supraventricular Tachycardia by wOmen OPerators: the STOOP Multicentre Registry (2026, Prospective cohort study)
Decreased Operator X-Ray Exposure By Optimized Fluoroscopy During Radiofrequency Ablation Of Common Atrial Flutter (2018, Prospective cohort study)
Reducing radiation exposure during procedures performed in the electrophysiology laboratory (2017, Retrospective cohort study)
Near zerO fluoroscopic exPosure during catheter ablAtion of supRavenTricular arrhYthmias: the NO-PARTY multicentre randomized trial (2015, Randomized trial)

How this summary was made

ORSIF prepared this summary with AI assistance from the abstract of the paper. A program then checked that the passage supporting each finding appears word for word in that source. A person has not yet reviewed each summary, so read the original before relying on a number. ORSIF summarizes research and does not endorse any product or company. Report a problem with this summary.

Prepared November 3, 2026.