Research summary, narrative review, 2026

Sub-Zero: A Review of the Current Evidence and Evolving Technologies Enabling Zero‑Fluoroscopy Procedures

Miller L, Agarwal A, Masri A, Atreya AR, Apte NM. Pacing and clinical electrophysiology : PACE. 2026

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In plain language

This review reports that zero- or near-zero fluoroscopy electrophysiology procedures using electroanatomic mapping and intracardiac echo achieve outcomes similar to standard fluoroscopy with much less radiation, though some procedures still need fluoroscopy and randomized evidence is limited.

At a glance

Type of study
Narrative review
Who was studied
Electrophysiologists, Patients
Summary based on
the abstract

What it found

  • Zero- or near-zero fluoroscopy workflows are reported to achieve procedural success, complication rates and long-term outcomes comparable to fluoroscopy-guided procedures while substantially reducing radiation exposure.

  • Reduced fluoroscopy is described as mitigating occupational risks including malignancy, cataract and orthopedic injury.

  • Zero-fluoroscopy workflows bring their own challenges, including vascular access complications, catheter thrombus and navigation errors.

  • Some complex procedures still rely on fluoroscopy, and operator experience and fluoroscopic bailout strategies remain important.

  • The authors call for standardized training and robust randomized studies.

Limits to keep in mind

Narrative review summarized from the abstract only; no quantitative data, search methods or included study counts are reported, and health-risk reductions are inferred rather than measured.

How this summary was made

ORSIF prepared this summary with AI assistance from the abstract of the paper. A program then checked that the passage supporting each finding appears word for word in that source. A person has not yet reviewed each summary, so read the original before relying on a number. ORSIF summarizes research and does not endorse any product or company. Report a problem with this summary.

Prepared November 3, 2026.