Research summary, systematic review or meta-analysis, 2022

Comparison of radiation exposure associated with transradial and transfemoral access: An updated meta-analysis

Saqib N, Pir MS, Rajagopalan S, Patel TM, Pancholy SB. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2022

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In plain language

In trials of coronary procedures, radial access added about 37 seconds of fluoroscopy time compared with femoral access, with no significant difference in dose area product; the gap has shrunk over time. Staff dose was not measured directly.

At a glance

Type of study
Systematic review or meta-analysis, Meta-analysis
Who was studied
Patients
Size
n = 11,611 patients (8 RCTs)
Summary based on
the abstract

What it found

  • Transradial access had slightly longer fluoroscopy time than transfemoral access in randomized trials.

    Key figures: WMD 0.62 min (37 s) (95% confidence interval (CI): [0.08-1.17], p = 0.023)

  • No significant difference in dose area product between access routes.

    Key figures: WMD 1.94 Gy.cm2 (95% CI: [-2.1 to 5.9], p = 0.35)

  • The fluoroscopy time gap between radial and femoral access has narrowed over time.

    Key figures: 1.6 min (96 s) in 1996 to 0.5 min (30 s) in 2020

  • The fluoroscopy time difference was larger in US studies than in studies from outside the US.

    Key figures: 0.88 min (52 s) outside US vs 2.1 min (126 s) US

  • Pooled observational and randomized data (83,990 patients) showed a similar trend.

    Key figures: 83,990 patients

Limits to keep in mind

Outcomes are patient-level surrogates (fluoroscopy time, dose-area product (DAP)) rather than measured staff dose; operator exposure was not directly assessed, and the abstract gives limited detail on heterogeneity and study quality.

How this summary was made

ORSIF prepared this summary with AI assistance from the abstract of the paper. A program then checked that the passage supporting each finding appears word for word in that source. A person has not yet reviewed each summary, so read the original before relying on a number. ORSIF summarizes research and does not endorse any product or company. Report a problem with this summary.

Prepared November 3, 2026.