Research summary, narrative review, 2012

Cancer and non-cancer brain and eye effects of chronic low-dose ionizing radiation exposure

Picano E, Vano E, Domenici L, Bottai M, Thierry-Chef I. BMC cancer. 2012

Read the original paper

In plain language

This review argues that the head and brain of interventional cardiologists and staff can receive substantial cumulative radiation, that evidence on brain cancer and cognitive effects is suggestive but inconclusive, and that head protection and systematic health studies are needed.

At a glance

Type of study
Narrative review
Who was studied
Interventional cardiologists, Interventional radiologists, Mixed lab staff
Summary based on
the full text

What it found

  • Without protection, lifetime head dose for a busy interventional cardiologist may reach 1 to 3 Sv, corresponding to a brain dose around 500 mSv.

    Key figures: 1 to 3 Sv head; ~500 mSv brain

  • Head organ dose in interventional cardiologists is 10- to 20-fold higher than the dose recorded beneath the apron.

    Key figures: 10- to 20-fold

  • Epidemiologic evidence for brain cancer in fluoroscopists is suggestive but not conclusive; a reported cluster of four brain tumours in interventional cardiologists were all left-sided.

    Key figures: 3 gliomas and 1 meningioma, all left-sided

  • Cataracts may be found in up to half of interventional cardiologists; lead eyeglasses reduced eye dose per coronary angiography from 165 to 37 μSv.

    Key figures: up to 50%; 165 μSv vs 37 μSv

  • Ceiling-suspended screens, lead caps or a radioprotection cabin greatly reduce scatter dose to the head.

    Key figures: factor of 2000; >100 μSv to 1 μSv per procedure

Limits to keep in mind

Narrative review without systematic search; brain cancer evidence in fluoroscopists relies on small case-control studies with wide confidence intervals and anecdotal case clusters, and neurocognitive effects are extrapolated largely from animal and high-dose data.

How this summary was made

ORSIF prepared this summary with AI assistance from the full text of the paper. A program then checked that the passage supporting each finding appears word for word in that source. A person has not yet reviewed each summary, so read the original before relying on a number. ORSIF summarizes research and does not endorse any product or company. Report a problem with this summary.

Prepared November 3, 2026.