Research summary, original research, 2017

Radiation-associated lens changes in the cardiac catheterization laboratory: Results from the IC-CATARACT (Cataracts Attributed to Radiation in the Cath lab) study

Karatasakis A, Brilakis HS, Danek BA, Karacsonyi J, Martinez-Parachini JR, Nguyen-Trong PJ, et al.. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2017

Read the original paper

In plain language

Among 117 conference attendees, interventional cardiologists and cath-lab staff with occupational radiation exposure had more lens changes than unexposed controls (47% vs 17%). These were mostly subclinical, and frank cataract rates did not differ significantly.

At a glance

Type of study
Original research, Cross-sectional survey
Who was studied
Interventional cardiologists, Mixed lab staff
Size
n = 117 participants
Summary based on
the abstract

What it found

  • Cortical and posterior subcapsular lens changes, including subclinical findings, were more common in exposed cath-lab participants than in unexposed controls.

    Key figures: 47 vs. 17%, P = 0.015

  • Occupational radiation exposure and age over 60 were independent predictors of lens changes.

    Key figures: Odds ratio (OR) 6.07 [1.38-43.45] for exposure; OR 7.72 [1.60-43.34] for age over 60

  • Frank lens opacities were uncommon, and their prevalence did not differ significantly between exposed participants and controls.

    Key figures: 14 vs. 6%, P = 0.461

  • Most lens findings were subclinical changes in the lens periphery that did not affect visual acuity.

Limits to keep in mind

This was a small cross-sectional convenience sample recruited at a conference, with only 18 controls who were younger and less often male than exposed participants, and exposure was assessed by questionnaire. The wide confidence intervals reflect imprecision.

How this summary was made

ORSIF prepared this summary with AI assistance from the abstract of the paper. A program then checked that the passage supporting each finding appears word for word in that source. A person has not yet reviewed each summary, so read the original before relying on a number. ORSIF summarizes research and does not endorse any product or company. Report a problem with this summary.

Prepared November 3, 2026.